|

In
these first decades of the biotech century, our way of life
will change more than in the previous thousand years. These changes offer
promises, such as bioremediation and alternative fuels and energy, but
also dangers, such as hazards to the biosphere and threats of biological
warfare. Nowhere will the effects be greater than in medicine and human
health. For example, new diagnostic tools resulting from the Human Genome
Project will vastly enhance our ability to predict the onset and progression
of disease. The current trial-and-error approach for disease treatment
will be replaced by drugs with unprecedented specificity, efficacy and
safety.
The surprisingly small number of genes found in the
human genome sequence has revealed that the higher level of complexity
lies at the protein level. Thus, when the human genome sequence was announced,
the human proteome — all the proteins contained
in a cell or organism — project was initiated
as the next step.
The genome project involved dozens of sequencing centers in many countries
and both academia and industry. The human proteome project will be far
more complex and will require far more interdisciplinary teams involving
molecular biology, genetics, bioinformatics, nanotechnology, medicine,
engineering, robotics, chemistry, physics, materials science and many
others. The projectwill require teams of researchers from academia, industry
and government laboratories from all over the world.
The UNT Health Science Center at Fort Worth will be
a part of this effort, and the focus of these activities will take place
in the Biotechnology Research Center now being planned. The center will
house an entire spectrum of activities, from basic to applied scientific
research, involving both academia and industry. Translational research
will allow discoveries to progress through development, prototyping and
clinical trials to minimize costs and development time for new drugs and
medical devices. This will speed the processes of "discovery to bedside."
The center will be home for the Health Science Center's
multidisciplinary Institutes for Discovery. The DNA Identity Laboratory
and the biotechnology graduate program will be located there. It will
also provide space for the Fort Worth Med Tech Incubator (where discoveries
are spun off into new biotech companies), research facilities for corporate
research partners and core facilities for genomics, proteomics, microscopy,
imaging and others. The Biotechnology Research Center will exemplify the
multidisciplinary team research paradigm of the biotech century.
|